M M & I 341 Study Guide - Midterm Guide: Clonal Selection, Natural Killer Cell, C3B
30 Oct 2014
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70%mc, 30% short answer, 90% from learning objective. Innate: vasc: dialation, increase blood flow, inc permeabilt- fluid leak out, upreg of ad mol wbc and endothelial- tight binding to go thru, neut most important. Cytokine: tlr cause release of ck, recognition mol for innate (along with phag) Complement bound to pathogen to complement on cell- rec med endo. All bact are phagocytized but only some can evade destruction. Inflammatory response includes acute phase- ck in blood to live and induce acute phase proteins. Most pathogens suppress inflamm response and avoid it. Inflammation is good but causes pain, medicine there is a balance bw treating inflammation and letting it progress. Nk- operate on inhibitory and non-inhib receptors, activating rec is engaed, normal engage inhibit.
