PSYCH 454 Study Guide - Midterm Guide: Local Field Potential, Pocket Cube, Voxel

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Extracellular electrode- reflects up to 1000 cells derived from within. Lfp recording: don"t see ap, see fluctuations and rhythmic portions. Reflects activity of a population of cell recordings. Ecog : brain surface recordings; common in epilepsy patients/research. Localize part of brain causing seizures identify damaged tissue place electrodes wait for seizure to localize exact spot of damage tissue + what to remove to prevent seizures. Summation of synchronized activity of neurons within same spatial orientation. Predominantly derived from pyramidal cells in cortex. Advantage : measure healthy subjects; non invasive (cap) Reflects 100s of thousands - millions of cells. Disadvantage : skull smears harder to assign signals to particular part of brain. Deep brain structures = inaccessible , only surface/cortical activity. Much smoother read (due to poor spatial resolution ridding of noise) Bold signal lfp spikes right before high bold. Visual stimulus presented, bold spikes couple seconds later, returns to normal after 10-15 seconds.