Biology And Biomedical Sciences BIOL 2960 Study Guide - Midterm Guide: Tumor Suppressor Gene, Dna Mismatch Repair, Pribnow Box
6 Feb 2019
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Bio2960 2010 exam study guide lectures 22-28: in class we discussed four dna repair pathways. For each, describe the damage targeted by the pathway and the steps in the pathway used to execute the repair of the damage. The best way to describe the steps is to diagram them on a piece of paper or chalkboard. Your description should also include the enzymatic activities needed to execute the steps; they should follow from the changes in the dna substrate that constitute the repair steps. Key terms: mismatch repair: mut proteins (muts protein identifies mismatched pairs -> recruits mut. What are the steps in the activation of the checkpoint and what are the practical consequences of it induction by dna damage. Key terms: damage induced protein kinase, checkpoint kinase, p53, p21, cyclin/cyclin- dependent kinase (cdk) complex, restriction point, rb protein. Key terms: the promoters most common to prokaryotes are the -10 sequence (pribnow box) and the.
