Biology And Biomedical Sciences BIOL 2960 Study Guide - Final Guide: Short-Chain Fatty Acid, Tumor Suppressor Gene, Butyric Acid
2 May 2016
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As soon as a baby is born, it is populated by microbes. Colonization occurs where the body meets the external environment: Eventually there will be 10 times as many microbial cells (most bacterial) than human cells in the body. New view: mutualistic interaction: both host and microbes benefit. Small intestine: absorption of monosaccharides, amino acids, fatty acids, water ph4. Large intestine: absorption of bile acids, vitamin b12 ph7. Targeting 16s rrna genes provides a idea of what is there. Bacteroides (a class) and clostridium (class) found in human gut. Sequencing microbial genomes helps determine what functions the community as a whole can perform. Can compare functional profiles between microbiomes of similar profiles. Individuals have variable ratios of firmicutes (~64%) and bacteroidetes (~23%), but they carry out the same important functions. Factors that influence the composition of the human gut microbiome: Influenced by development, changes in diet, and life events.
