BIOL1003 Chapter 9: BIOL1003, Chapter 9
Document Summary
Franklin and wilkins: x-ray crystallogram of dna. Watson and crick (structure of dna: used c-ray data from franklin, wilkins and gosling, knowledge of chemical composition of dna, built models, had no real evidence for their structure. O(cid:374)e e(cid:374)d of each stra(cid:374)d has a free (cid:1009)" phosphate group. Two strands are linked by hydrogen bonds between bases. Occur between an electronegative and a h atom. [unreadable] info is stored in dna: dna is a macromolecule. Changes to the sequence of monomers in a polymer. Genetic variation occurs as a result of changes to the information. Hierarchy of three polymers: genotype carried in the dna & proteins determine the phenotype, rna transfers info from dna proteins. Protein: worked with the fungus, neurospora, wild type neurospora. Prototroph can synthesize all organic molecules required for growth from sugars and inorganic ions: selected mutants that were auxotrophs, each auxotrophic mutant tested to find out which organic molecules had to be supplied.
