CHEM 1004 Chapter Notes - Chapter 6: Orphan Receptor, Oxycodone, Dextromethorphan
1 May 2014
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Chapter 6 - narcotic analgesics: opiates and opioids: can ease childbirth. Alkaloids - basic nitrogen containing compounds that are found in plants and that produce physiological reactions of various kinds and intensity ex. Narcotic - is a substance that provides a stupefying, dulling effect that induces sleep. Not all pain killers are narcotics; ex. codeine doesn"t induce sleep. Opiate - any narcotic derived from opium: morphine, codeine, heroin. Opioid - any synthetic narcotic that has opiate-like pharmacology, but is not derived directly from opium: ie, naloxone, methadone. Pros: one of the most powerful analgesics known, soothes and calms, and cough suppressant by depressing the couch center. Cons: confusion, euphoria, depresses respiratory system, chronic constipation, lethargy. Binds to opiate receptor site in brain but doesn"t interfere with the transmission of pain. Not maximally effective when taken orally, use pumps after surgery. Does not cause tiredness and is in cough syrups. Causes euphoria (happy), stupor (lack of cognitive function) and analgesic.
