NURS 2112 Chapter Notes - Chapter chapter 13 pathophysiology-fifth edition: Disseminated Intravascular Coagulation, Hemolytic Anemia, Central Venous Pressure

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Blood loss anemia presents after a trauma or secondary to a disease process. Rapid decrease in the overall blood volume and impairs oxygen delivery to the body. Clinical manifestations; 10% of blood loss usually does not cause clinical presentation, usually only occasional vasovagal syncope. 20% blood loss shows as tachycardia with exercise, and a slight postural drop in blood pressure occurs. 30% loss usually presents with flat neck veins when supine, postural hypotension, and exercise tachycardia. 40% loss causes the central venous pressure, cardiac output, and arterial blood pressure to fall below normal while the patient is supine and at rest with associated air hunger, tachycardia, and cold, clammy skin. 50% loss of total blood volume often causes shock and death. When fetal red cells cross the placenta, they may stimulate the production of maternal antibodies against antigens on the fetal red cell not inherited from the mother.

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