NURS 3102 Chapter Notes - Chapter 39.2: Creatinine, Chronic Kidney Disease, Nephron
17 Feb 2017
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Identify and contrast pre renal, intra renal, and post renal failure. Pre renal: hypoperfusion of kidney, occurs as a result of impaired blood flow that leads to hypoperfusion of the kidney and a decrease in gfr, common clinical situations include: Impaired cardiac performance (myocardial infarction, heart failure, or cardiogenic shock) Intra renal: actual damage to the kidney tissue, the result of actual parenchymal damage to the glomeruli or kidney tubules, conditions such as: With burns and crush injuries, myoglobin ( a protein released from muscle when injury occurs) and hemoglobin are liberated, causing obstruction, renal toxicity, and ischemia. May lead to acute tubular necrosis (atn) and cessation of renal function. May cause intrarenal failure: hemoglobin is released through hemolysis, filters through the glomeruli, and becomes concentrated in the kidney tubules to such a degree that precipitation of hemoglobin occurs. Medications predisposing to intrarenal damage such as:
