BIOL 1051H Chapter Notes - Chapter 7: Adipose Tissue, Central Canal, Osteoclast

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14 May 2018
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Bone Tissue
Bone tissue is a specialized type of connective tissue that includes calcium, phosphorus,
and other minerals in the ground substance resulting in a very hard tissue. Bone is one of many
tissues found in the skeletal system. Other tissues found in the skeleton are blood, adipose
tissue, bone marrow, nervous tissue, cartilage, and fibrous connective tissue. This system
includes bone, cartilage, and ligaments. Cartilage is the embryonic forerunner of most bones
and covers many joint surfaces, ligaments hold bone to bone at joints, and tendons are much
like ligaments only they attach muscles to bone. The skeletal system obviously has the role of
providing support for the rest of the body, but it has many other important functions as well. The
addition of the muscular system provides the basis for movement. Some areas of the skeleton
are especially important for protecting vulnerable underlying organs such as the skull and rib
cage. The red bone marrow is the site of blood formation. Calcium and phosphorus are stored
as bone. The interplay of these chemicals moving from a solid form (bone) to the dissolved
liquid form in blood helps with electrolyte balance and in maintaining acid - base balance in the
body. The bone can also serve as a site of toxin deposition and can help detoxify the body by
removing these chemicals from general circulation.
Bone tissue involves many cell types such as osteogenic cells (stem cells), osteoblasts
(bone forming cells), osteocytes (bone cells), and osteoclasts (bone dissolving cells). All of
these cells work together to produce and maintain healthy bone tissue. The osteoclasts and
osteoblasts are also intimately involved in maintaining normal calcium blood levels by either
depositing calcium in bone or reabsorbing calcium into the blood. The diagram below shows
these different cells in action. Please note that as the osteocytes produce the bone matrix, they
actually become trapped in the tissue! These cells receive the nutrients and gases they need via
the lacunae. When bone is reabsorbed by osteoclasts they work from the outside of the bone in.
They breakdown the matrix and destroy osteocytes that are in their way. It seems really
destructive, but the constant interplay between bone deposition and reassertion keeps the bone
healthy. It is also important in healing of injuries such as fractures in they will continue to
remodel and be better at dealing with forces that result from weight and movement. It can take
years for fractures to finish this remodeling phase, and often the resulting bone does not show
any signs of having ever been broken.
Bone itself can be found as compact bone or spongy bone. Compact bone is organized
into a haversian or osteonic canal system. Layers of bone matrix are concentrically arranged
around a central canal. The central canal contains blood vessels and nerves that traverse the
bony tissue. An osteon (the haversian system) contains a central canal and the layers of
concentric lamellae that wrap around it. Compact bone is a dense white tissue that acts as an
outer shell. Here it is shown as part of a long bone but it is also found in intramembranous
bones as well. Compact bone comprises about ¾ of the skeleton.
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Document Summary

Bone tissue is a specialized type of connective tissue that includes calcium, phosphorus, and other minerals in the ground substance resulting in a very hard tissue. Bone is one of many tissues found in the skeletal system. Other tissues found in the skeleton are blood, adipose tissue, bone marrow, nervous tissue, cartilage, and fibrous connective tissue. Cartilage is the embryonic forerunner of most bones and covers many joint surfaces, ligaments hold bone to bone at joints, and tendons are much like ligaments only they attach muscles to bone. The skeletal system obviously has the role of providing support for the rest of the body, but it has many other important functions as well. The addition of the muscular system provides the basis for movement. Some areas of the skeleton are especially important for protecting vulnerable underlying organs such as the skull and rib cage. The red bone marrow is the site of blood formation.

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