HSS 3106 Chapter 16: Antibacterial Agents

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Infection is the most common cause of death for many ppl with chronic or critical illnesses, and the very young/very old ppl are most susceptible; caused by microorganisms that enter body. Transmission of infection requires unbroken chain of events: pathogenic organism must live and reproduce in a reservoir i. e human being, and animal, soil, need a certain amount of pathogens to develop an infection/sickness. Influenza virus is example of an organism that reproduces in a human being: pathogen needs portal of exit and mode of transmission from reservoir to susceptible victim i. e exit via nasal mucosa, transmit via nasal droplets. Handwashing frequent handwashing with soap, friction, and warm running water is one of the most effective ways to reduce pathogenic transmission. Interactions with cyclosporine can cause toxicity: macrolides azithromycin (zithromax), clarithromycin (biaxin), erythromycin base (e-mycin) Fluoroquinolones: mechanism of action interfere with dna gyrase (enzyme required by bacteria for synthesis of.

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