BIO152H5 Chapter Notes - Chapter 12: Sister Chromatids, Spindle Apparatus, Nuclear Membrane

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16 Jan 2014

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Homologous chromosomes (homologs): two chromosomes of each type. Carry same genes but may carry different alleles. Diploid: two versions of each type of chromosome. Two alleles of each gene; one on each chromosome. Haploid number (n): the number of distinct types of chromosomes in a given cell. Diploid number (2n): number of chromosomes present in a diploid cell ex humans have 46. Combination of a number and n is termed the cell"s ploidy. Polyploid: 3 or more of each type of chromosome. Unreplicated and replicated chromosomes are each considered single chromosomes even though the replicated chromosome comprises two sister chromatids. Unreplicated chromosome: a chromosome that consists of a single copy. Replicated chromosome: has been copied; consists of two linear structures joined at the centromere. Sister chromatids: the chromosome copies in a replicated chromosome. Non-sister chromatids: the chromosome copies in homologous chromosomes. When two gametes fuse during fertilization, a full complement of chromosomes is restored.

Related Questions

M2A1 Worksheet: Mitosis and Meiosis

A dog is a diploid organisms and has 39 pairs of chromosomes (2n = 78), where n = 39 chromosomes from each parent. Use this example to answer the following question regarding chromosomal number.

INTERPHASE

How many chromosomes are present in the somatic cell?

What do they look like?

What are they âdoingâ in G1 of this phase?

What is happening in the S phase?

What is happening in the G2 phase?

What follows G2 phase in a somatic cell?

What follows G2 phase in a gamete cell?

MITOSIS

Number of chromosomes in the parent cell.

Number of chromatids in the parent cell.

Number of chromosomes in the daughter cell.

Number of chromatids in the daughter cell.

How many daughter cells are produced?

Are the daughter cells haploid or diploid?

How many cell divisions take place?

In what type of cell does this division occur?

Meiosis 1:

Number of chromosomes in the parent cell.

Number of chromatids in the parent cell.

Number of chromosomes in each Meiosis I daughter cell.

Number of chromatids in each Meiosis I daughter cell.

Are the daughter cells haploid or diploid at the end of Meiosis 1?

Meiosis II:

Number of chromosomes in the âparentâ cell (which is a daughter cell from Meiosis I).

Number of chromatids in the âparentâ cell.

Number of chromosomes in each Meiosis II daughter cell.

Number of chromatids in each Meiosis II daughter cell.

Are the daughter cells haploid or diploid at the end of Meiosis II?

Which phase or phases of Meiosis account for the genetic variability among the daughter cells? Howâ¦ what happens in this phase to create the diversity?

Comparing Mitosis and Meiosisâ¦..

How many daughter cells result from Mitosis? Are they diploid or haploid?

How many daughter cells result from Meiosis? Are they diploid or Haploid?

Cell structures and function: Match each organelle to its function:

Organelle Function

Lysosome 1. Lipid synthesis

Rough ER 2. Houses DNA

Nucleus 3. Energy extraction

Smooth ER 4. Dismantles debris

Golgi apparatus 5. detoxification

Mitochondria 6. Protein synthesis

Peroxisome 7. Processes secretions

What is the function of checkpoint proteins in the cell cycle?

How can all of a personâs cells contain exactly the same genetic material, yet specialize as bone cells, nerve cells, muscle cells and connective tissues?

What are the 3 primary germ layers?

Briefly, in one or two sentences, distinguish between

a bacterial cell and a eukaryotic cell

interphase and mitosis

mitosis and apoptosis

an autosome and a sex chromosome

homologous pair of chromosomes and a sister chromatid

centromere and centriole

chromosome and chromatid

monozygotic and dizygotic twins

allele and gene

Match the term with its correct definition or explanation.

Chromatin

Homologous Chromosomes

Sister chromatids

Diploid

Interphase

S Phase

Synapsis

Crossing Over

Cell Plate

Cleavage Furrow

A. The exchange of genetic material between homologous chromosomes during meiosis I.

B. The pairing or tight association of homologous chromosomes in meiosis I. Results in the formation of a tetrad.

C. Non-identical copies of the same chromosome. Present in all diploid cells, even before replication. These chromosomes are the same length and contain genes for the same characteristics, but may have different alleles for each gene. D.

The period of the cell cycle that includes G1, S phase, and G2. E. A structure that develops during cytokinesis in plants.

F. Condensed chromosomes.

G. An invagination that develops during cytokinesis in animal cells.

H. When an organism has two copies of every chromosome (2n).

I. Two identical copies of a chromosome. These are only present after DNA replication.

J. The phase of the cell cycle when DNA is replicated.

Ploidy refers to the number of complete sets of chromosomes (genes) present in a cell. The number of chromosomes in a complete set is a fixed characteristic of a species. Humans are diploid with two sets of 23 chromosomes. Fruit flies are diploid with two sets of 4 chromosomes. Sexually reproducing organisms are diploid, each somatic cell of an organism has two complete sets ("di" is a prefix indicating 2.). To complete a life cycle and reproduce new members of a species, mating is required. Mating brings a donation from a male and a donation from a female together. However, if the male and female cells remain diploid, the fertilization will result in a tetraploid zygote. In general, these are not viable. A mechanism is needed to form special haploid cells, gametes. The diploid set is split precisely into two complete haploid sets. That mechanism is meiosis.

The complete set of chromosomes of a species is also the complete set of genes of a species, the genome. (Yes, there is a minor contribution from mitochondria and chloroplasts. Inheritance of this information is "cytoplasmic".)

Please answer the following questions:

1. How many chromosomes in a brain cell of a fruit fly? How many chromosomes are in a liver cell of a human? Explain both answers.

2. How many chromosomes are in a fruit fly unfertilized egg? How many chromosomes are in a human egg? Explain both answers.

3. Why is meiosis necessary for sexually reproducing organisms? How many chromosomes are in a human zygote? Relate the two answers.

4. What is a gene allele? Suppose there is a gene called "bingo" and it is present once in a complete haploid set. How many alleles of "bingo" does a diploid individual have? How many copies or versions of the gene "bingo" are present in a diploid individual?

5. Modern DNA sequencing clearly identifies alleles by showing the different DNA sequence of each allele. These alleles may be termed structural alleles (I coined the term for this problem.). Classical genetics only dealt with phenotypes or visible traits. As a result, alleles of genes were identified by functionality, usually normal or non-functional. Using your knowledge of gene structure and gene expression, postulate a relationship between structural alleles and functional alleles. (include relative amounts; more, less, or equal).

BIO152H5 Chapter Notes - Chapter 12: Sister Chromatids, Spindle Apparatus, Nuclear Membrane

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