BIO207H5 Chapter Notes - Chapter 5: Quantitative Trait Locus, Quantitative Genetics, Variance
Document Summary
Continuous traits exhibit few distinct phenotypes continuous or quantitative traits display a range of phenotypes have a range of phenotypes. Variation can be partitioned into genetic & environmental components. Amount that a trait changes in one generation as a result of selection on the trait is called the response to selection. Magnitude of the response to the selection depends on the selection differential & narrow-sense heritability. Genetic correlations arise when 2 traits are influence by the same genes or linked genes trait is selected, genetically correlated traits also exhibit a response to selection. Quantitative trait loci determine continuous traits can be identified through marker-based mapping. Qtl mapping provides estimate of the number & relative importance of genes influencing quantitative genetic variation. Discontinuous traits simple relationship exists between genotype & phenotype. Francis galton & karl pearson demonstrated that many traits in humans such as weight, height, & mental traits, the phenotypes of parents & their offspring are statistically associated.