BIOL 2020 Chapter Notes - Chapter 8: Dosage Form, Fluticasone Propionate, Propranolol
20 Apr 2020
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Document Summary
Solvents can bring chemicas in contact w/compound to cause rxn like hydrolysis, decomposition. Some tablets sealed in blister if moisture sensitive. Liquids may not have accurate dosing due to different measuring spoons. 70% of all medicines are solid dosage forms. Stable, accurate dose, compact, simple to make (except for inhalation) Tablets & inhalation powders are tricky to formulate. Want to make sure tab dissolved within a time: restricted to few routes of administration no iv, don"t want dose to be +/- 10, not suitable for injections, ophthalmic solutions. Crushing, grinding tab, mixing w/water to inject can form suspension causing embolism. Capsules can contain granules of various medication in one for seniors. Emulsions: when 2 immiscible liquids are led by another liquid. Suspensions : heterogenous mix that contains solid particles that can sedment. Particles are visible, larger than 1 micrometer: ointments: a semisolid consisting medical substances mixed in based. Ointment bases could be hard paraffins, emulsion of o/w.
