PHIL 2015 Chapter Notes - Chapter 2.6: Cholecalciferol, Basal Metabolic Rate, Tretinoin
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Triiodothyron ine, t3 and thyroxine, t4 (less active) Levothyroxine (synthetic t4), mixtures of t3 & t4. Tr 1 widely expressed and esp high expression in cardiac and skeletal muscles. Tr 2 widely expressed but unable to bind hormone. Note: ptu and methimazole inhibit production of thyroid hormones and have. 1,25- dihydroxy vitamin d3 (calcitrol; synthesized from vitamin. Regulation of calcium and phosphorus absorption and homeostasis. Critical for embryonic development, maintenance of visual pigments, maintenance of skin. Early observation: caused proliferation of peroxisomes in mouse. Many cosmetics contain low amounts of retinoids can be dangerous at high doses. Ppar : promotes uptake, utilization, and catabolism of fatty acids in liver by upregulating genes involved in fatty acid transport and mitochondral fatty acid -oxidation. Ppar : may be an important regulator of cholesterol trafficking in macrophages, promotes formation of. Type 1 muscle fibres (good for long distance running)