SOCI 3630 Chapter Notes - Chapter 8.2: Hacek Organisms, Kingella Kingae, Cardiobacterium Hominis
4 Jun 2020
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Ie = inflammation of the endocardium, membrane lining of the chambers and the covering of the cusps of heart valves. Acute ie more severe & if untreated death can occur in a few days. Subacute ie indolent & caused by less aggressive organisms (viridans strept) & usually occurs in pre-existing heart disease. Most cases occur in ppl > 50yo (this age has increased over the last 30 yrs) Native valve ie: most freq (70-90%, community acquired or hospital acquired. Prosthetic valve ie: frequency = 20-30, seen in older pop. w/ co-morbidities and prosthetic valves (inc. pacemakers & defibrillators, early: < 2 months after surgery, late: >2 -12 months after surgery. Pve pathogenesis is different b/c surgery may directly inoculate the valve w/ bacteria from patient"s skin or or. This new valve is more prone to bacteria colonization. Bacteria in the vegetation grow slowly and are protected from abx & host defenses.
