BIOL 300 Chapter Notes - Chapter 2: Cell Cycle, Cell Division, Meiosis
Document Summary
Cell cycle has many internal and external regulatory mechanisms which control mitotic cell cycle. As part of the internal controls , cell cycle has built in checkoints. These checkpoints , prevent critical phases from beggining until the previous phases are completed ( by using hormones, growth factors , etc) Cyclins and cyclin dependent kinases are the internal controls that directly regulate cell division. Cyclin -dependant kinases (cdk): major players in regulation of cell division, directly affecting progression through the cell cycle. Protein kinases, enzymes that add phosphate to target protein groups. Switched on only when combined with protein called cyclin. Replication of the bacterial chromosome begins at a site called the origin , through reactions catalyzed by enzymes located in the middle of the cell. Once the origin of replication is duplicated, the two origins migrate to the two ends of the cells.
