ENG BE 209 Chapter Notes - Chapter 17: Myofibril, Centrosome, Dynein
30 Jul 2018
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Document Summary
Cytoskeleton: an intricate network of protein filaments that extends throughout the cytoplasm. Intermediate filaments: have great tensile strength and their main function is to enable cells to withstand the mechanical stress that occurs when cells are stretched. Found in the cytoplasm of most animal cells. Often anchored to the plasma membrane at cell-cell junctions such as desmosomes. Mesh of intermediate filaments, the nuclear lamina, underlies and strengthens the nuclear envelope in all eukaryotic cells. Prominent in the cytoplasm of cells that are subject to mechanical stress. Abundant in muscle cells and in epithelial cells. Vimentin and vimentin-related filaments in connective-tissue cells, muscle cells, and supporting cells of the nervous system. Nuclear lamins which strengthen the nuclear membrane of all animal cells. The nuclear envelope is supported by a meshwork of intermediate filaments. Disassembly and reassembly of the nuclear lamina are controlled by the phosphorylation and dephosphorylation of the lamins by protein kinases.
