CAS BI 108 Chapter Notes - Chapter 11: Cyclin D, Protein Kinase, P53
Document Summary
Cell replication: reproductive signal, genomic replication, segregation, cytokinesis. Cell cycle: the life of single cells form the completion of one division to the next. Cells grow, function, and replicate their chromosomes during this cycle. The purpose is for growth, function, and commitment to another cell division. Cell fusion regulates cell cycle: interphase o most of the life of the cell, the phase between mitotic divisions, the time between the end of one mitotic cycle and the start of another (23 hours) Cells can leave cell cycle or progress during this time. Restriction point (commitment) is where the cell cycle is inhibited of proceeding by testing the environment. If signal is positive, then the cell will proceed, if not, the cyclins will be destroyed because it is no longer needed transition of cyclins in g1 is activated by nutrients and growth factors. By inhibiting the inhibitor, the cell cycle is allowed to proceed.