CAS BI 325 Chapter Notes - Chapter 4: Dramatic Structure, Optogenetics, Resting Potential
2 Jan 2018
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Action potential = a spike = nerve impulse - discharge. During an action potential, when the inside membrane is positive w respects to the. Action potential: (1) thumbtack (2) nerve fiber membranes in skin stretch (3) na+ permeable channels open. --large concentration gradient, negative inside mem, na+ crosses through the channels. ***na+ caused depolarization in this example, but diff neurons receive action potentials different ways. Optogenetics: that will open in response to light. **depolarization of the cell during an action potential is due to to influx of sodium (na+) ions across the membrane, and repolarization is caused by the efflux of potassium (k+) ions. Voltage gated na+ channel opens/closes based on changes in membrane voltage. Foreign genes introduced into neurons that can express membrane ion channels. Ion-water complex w/ na+. allows channel to be selective for na+ and selective against k+ Single a. a. mutation in extracellular region of sodium channels shows common inherited disorder in infants: .
