BIOMG 1350 Chapter Notes - Chapter 4, 17: Atp Hydrolysis, Motor Protein, Spindle Apparatus

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Atp hydrolysis allows motor proteins to produce directed movements in cells: conformational changes also allow specialized proteins to drive cell movement, motor proteins. Intracellular movements of organelles and macromolecules: move chromosomes to ends of cells during mitosis, conformational changes allow protein to walk along cytoskeletal filament. Irreversibility of one conformational change achieved by hydrolysis of. Proteins often form large complexes that function as protein machines: more domains=more complex functions, protein machines. Large protein assembles formed by many protein molecules. Hydrolysis of bound atp or gtp drives conformational changes in individual protein subunits ensembles moves coordinately. Appropriate enzymes can be positioned to carry out successive. Crucial organizing roll in eukaryotic cells reactions in a series: long, relatively stiff hollow protein tubes, rapidly disassemble in one location, and reassemble in another, grow out from centrosome. Small structure near center of the cell: create a system of tracks for organelles, vesicles, and macromolecules, mitotic spindle.

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