MCB 3020 Chapter Notes - Chapter 15: Tautomer, Dna Replication, Concept Map
Document Summary
Mechanisms of genetic variation: distinguish spontaneous from induced mutations, and list the most common ways each arises, construct a table, concept map, or picture to summarize how base analogues, Dna-modifying agents, and intercalating agents cause mutations: discuss the possible effects of mutations. Chemical basis and effects: stable, heritable changes in sequence of bases in dna. Spontaneous mutations: arise without exposure to external agents, may result from errors in dna replication. Due to base tautomerization resulting in transition and transversion mutations. Due to insertion or deletion of nucleotides: may also result from the action of mobile genetic elements such as transposons. Induced mutations: caused by agents that directly damage dna. Mistakes occur when they are incorporated into growing polynucleotide chain. Alter a base causing it to mispair intercalating agents. Distort dna to induce single nucleotide pair insertions and deletions. Most prevalent form of gene: forward mutation. Wild type mutant form: reversion mutation.
