PCB 4674 Chapter Notes - Chapter 9: Genetic Recombination, Population Genetics, Meiosis

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The population genetics consequences of sex: sex (in a genetic and evolutionary sense) is defined as reproduction that involves both: Mutation, drift, inbreeding, and sex: example: c. elegans. Gene that maintains males at a frequency of 10-20% Population evolves by natural selection for 50 generations. Worms had to cross rugged terrain in order to find food. By making the worms cross an obstacle imposes selection against deleterious mutations. Fixed for a mutation lethal to males and thus consisted of obligatory selfing hermaphrodites: suffered a decline in fitness compared to ancestor- accumulation of deleterious mutations. Wild type and consisted of hermaphrodites and males: only modest gains in relative fitness- the males were able to help maintain the fitness of the population. Same three populations were then dosed with an artificial chemical mutagen every other generation for fifty generations- this mutagen increased mutation rate x4 each time it was applied.

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