PCB 4674 Chapter Notes - Chapter 1: Intracellular Parasite, Antibody, T Helper Cell
6 Jul 2016
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1. 1 the natural history of the hiv epidemic. First recognized in 1981, and the virus was identified in 1983: professionals predicted that a vaccine would be ready for testing within two years. Has infected over 65 million people and led to ~30 million deaths: 3. 1% of deaths worldwide. Lower respiratory tract infections (6. 1%: worst in sub-saharan africa. Worst in swaziland- 26% of adults are infected. The new infection rate is falling: infection rates higher in men who have sex with men and injection drug users. Bodily fluid carries virus from infected person directly onto a mucous membrane or into the bloodstream of an uninfected person: via semen, vaginal/anal secretions, blood and breast milk. Drugs exist that can reduce transmission rates: antivirals cut chance of mother-child transmission by 40, condom use can reduce risk by ~80% Intracellular parasite capable of reproducing on its own: invades specific immune system cells.
