BIOL 4570 Chapter Notes - Chapter 3: Adaptive Immune System, Mannose Receptor, Dendritic Cell
Document Summary
Induced responses of innate immunity: pattern recognition receptors ~ contrasted with antigen specific receptors of adaptive immunity. 3. 2 g protein coupled receptors on phagocytes link microbe recognition with increased. Phagocytes don"t produce toxic oxygen derivatives characteristic of respiratory burst and so are less able to kill ingested microorganisms and clear infection. Inflammation characterized by pain, redness, heat, and swelling at site of infection: functions, delivers additional effector molecules and cells from blood into sites of infection increases destruction of invading microorganisms. Induces local blood clotting to provide physical barrier to spread of infection in bloodstream: promotes repair of injured tissue, types of changes in local blood vessels. 3. 5 mammalian toll like receptors are activated by many different pathogen associated. 3. 6 tlr-4 recognizes bacterial lipopolysaccharide in association with host accessory proteins. 3. 7 tlrs activate transcription factors nf kb, ap-1, and irf to induce expression of.
