PSYC 3 Chapter Notes - Chapter 1: Hamilton Rating Scale For Depression, Psychomotor Retardation, Circadian Rhythm

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Unipolar depression mood disorder characterized by subnormal arousal. Dysfunction of the arousal systems that mediate emotion and motivation. Insomnia at night, hypersomnia during the day. Diminished ability to concentrate or sustaining attention. General anxiety is present in at least 50% Prevalence is about 6% in the usa. Females are about 2 times more likely than males. Higher among ages 20-40 yrs and low ses (economic disposition) Single or recurrent episodes of severe depression having a rapid onset and lasting 18-24 months (months to years) First episode is often triggered by a stressful event. Depressed patient has exhibited a 50% reduction in symptoms with treatment. Patient is well remission that is over 6 months. A worsening of symptoms after recovery has been reached. Biological explanation for depression emerged from discovery of two antidepressants the two drugs were: Lead to the monoamine hypothesis of depression irreversible mao inhibitor. Depression is caused by insufficient activity of the monoaminergic neurons.

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