BIOL 1201 Chapter : Lec13
Document Summary
Continue from bulk transport across the plasma membrane in lecture 12 study guide. Introduction to cellular metabolism: cells require constant input of energy, metabolic energy requires energy (endergonic) or release energy (exergonic, endergonic reactions are coupled to exergonic reactions. Atp hydrolysis powers cell - mechanical, transport, chemical processes (respiration and photosynthesis. Example: coupling of glutamine synthesis and atp hydrolysis. Reactions are catalyzed by enzymes: enzyme- proteins that function as biological catalyst, they lower the activation energy of a reaction, depend on their shape (conformation) for activity. Example of a reaction: beach, letter, bring desk easier to write/ desk acts as catalyst, 2h2o2====catalase== 2h2o+ o2 (substrates or reactants ) ==enzyme products. Factors affecting enzyme activity: temperature & ph, cofactors (inorganic metals, coenzymes, enzymes inhibitors. Examples: temperature and ph optima- best conditions for full enzyme function. 8. 17: compounds that bind with enzymes and inhibit activity, competitive inhibitor- active site is blocked, noncompetitive inhibitor- binds alternate site , alters protein shape.
