BIOL 1201 Chapter : BIOL 1201 2 28

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15 Mar 2019
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Substrate level phosphorylation: transfer of high energy phosphate to generate atp, kinases catalyze these reactions. Two turns of the krebs cycle per glucose molecule: pyruvate, 3-carbons, glucose, 6-carbons, co2, atp and reducing power, nadh and fadh2. Co2: produced at this step (but no o2 involved) Why is it a cycle: starting molecules are regenerated. Nadh and fadh are used to produce atp: in the mitochondrion, through oxidative phosphorylation, oxygen is used at this step to produce h2o. Atp production: atp from substrate level phosphorylation, known from stoichiometry, atp from oxidative phosphorylation, less certain because the stoichiometries of proton pumping, Atp syntheses, and metabolite transport processes need not be integer numbers or even have fixed values. Electron transport: electrons are passed downhill , reducing the complex which receives it, the uphill component, lower affinity for the electrons, small steps, reduction of o2. Hydrogen ion gradient: maintained by the exergonic flow of electrons in the electron transport chain.

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