PSYC 3458 Chapter Notes - Chapter pg. 67-78; 88-90; 92-96: Excitatory Postsynaptic Potential, Inhibitory Postsynaptic Potential, Axon Hillock
4 Jan 2018
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Inhibitory postsynaptic potential: a hyperpolarizing potential in the postsynaptic neuron that is caused by inhibitory connections. 73-78: synaptic transmission requires a sequence of events, 1. The action potential is propagated into the presynaptic axon terminal: 2. Voltage-gated calcium channels in the membrane of the axon terminal open, and calcium ions enter the axon terminal: 3. Calcium ions causes synaptic vesicles filled with neurotransmitter to fuse with the presynaptic membrane and rupture, releasing the transmitter molecules into the synaptic cleft: 4. Some transmitter molecules bind to special receptor molecules in the postsynaptic membrane, leading directly or indirectly to the opening of ion channels in the postsynaptic membrane. The resulting flow of ions creates a local epsp or ipsp in the postsynaptic neuron: 5. The ipsps and epsps in the postsynaptic cell spread toward the axon hillock, interacting with each other along the way.
