BIOLOGY 1113H Chapter Notes - Chapter 7: Lipid Bilayer, Fluid Mosaic Model, Endoplasmic Reticulum
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18 Sep 2016
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Selective permeability: allows some substances to cross it more easily than others. 7-1| cellular membranes and fluid mosaics of lipids and proteins. Lipids and proteins are staple ingredients of membranes, carbohydrates also important. Phospholipids have ability of phospholipids to form membranes due to molecular structure. Amphipathic: a molecule that has both hydrophilic and hydrophobic region. Most membrane lipids and membrane proteins are amphipathic and reside in phospholipid bilayer with hydrophilic regions protruding. Fluid mosaic model: membrane is a mosaic of protein molecules bobbing in a fluid bilayer of phospholipids. Proteins aren"t randomly distributed, groups form in long-lasting specialized patches. Membranes aren"t static, they"re held together primarily by hydrophobic interactions, much weaker than covalent bonds. Most lipids and some proteins can shift laterally (within plane of membrane); flipping from one phospholipid to another is not likely. Proteins are larger than lipids and thus don"t move as quickly. Some proteins move, others are immobile from being connected to cytoskeleton or extracellular matric.
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