NUR 1211C Chapter Notes - Chapter Test 3: Coronary Artery Disease, Coronary Circulation, Low-Density Lipoprotein
8 Feb 2020
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Document Summary
Cad may evolve to more serious conditions of unstable angina (ua) and myocardial infarction (mi), which are called acute coronary syndrome (acs) It is characterized by lipid deposits within the intima of the artery. Endothelial injury and inflammation play a central role in the development of atherosclerosis: c-reactive protein (crp), a protein produced by the liver, is a nonspecific marker of inflammation. It is increased in many patients with cad: chronic elevations of crp are linked with unstable plaques and the oxidation of low-density lipoprotein (ldl) cholesterol, developmental stages, fatty streak. Fatty streaks are characterized by lipid-fluid smooth muscle cells. Treatment that lowers ldl cholesterol may reverse this process: fibrous plaque. Ldls and growth factors from platelets stimulate smooth muscle proliferation and thickening of the arterial wall. Lipoproteins (carrier proteins within the bloodstream) transport cholesterol and other lipids into the arterial intima. Collagen covers the fatty streak and forms and fibrous plaque with a grayish or whitish appearance.
