01:119:131 Chapter Notes - Chapter 17: Innate Immune System, Mast Cell, Mucous Membrane

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Know the difference between innate defenses and adaptive defenses. Innate immunity is already present in the body. First line of defense when encountering a foreign pathogen. Adaptive defenses are only created when exposed to the foreign invader. Physical barriers- made of cells that line the body surfaces and secrete chemicals that make the surface hard to penetrate and inhospitable to pathogens. Mucous membranes cover tissues and organs of the body cavity that are exposed to the exterior. Mucus and hair in nasal and respiratory system. Coughing and sneezing; vomiting and diarrhea; tears and saliva; and urinating are examples of body mechanisms that clear the body from microbes. Sweat glands produce sweat that has a very high concentration of salt which inhibits many bacteria from growing. High ph of stomach protects against intestinal pathogens. Lysozyme, an enzyme present in tears, saliva, and mucus, cleaves peptidoglycan layers, thus inhibiting gram positive bacteria.

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