BIO 202 Chapter Notes - Chapter 12: Epigenetics, Cell Plate, Sister Chromatids

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After dna duplication- chromatin condenses to make a smaller package. Long linear dna molecules x ll l< >l: synthesis dna replication. Interphase: g1, s, g2 (everything other than mitosis: g2 centrosomes duplicate and grow microtubles out of them, mitotic chromosomes: (held like this as sister chromatids after synthesis until ready for separation) Sister chromatids: 2 copies of the replicated chromosome. Kinetochore: protein disc that binds mitotic spindle through cohesion the place where spindles hook on to pull it. Cohesion- complex of proteins holding replicated chromosomes together at their centromeres, until they are properly configured for separation (holding hands) (middle of x: mitotic spindle pulls sister chromatid apart. Origin of replication: site where dna gets replicated 2 origins detach from each other but not the plasma membrane. Bio 202 chapter 12 phemie chan. 1-3 are all part of interphase which accounts for 90% of the cell cycle: regulation of the cell cycle:

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