PY 105 Chapter Notes - Chapter 2: Resting Potential, Cell Membrane, Membrane Potential

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19 May 2018
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Neuronal Structure and Function
Neurons are specialized cells that transmit and process information from one part of the body to
another
Takes the form of an action potential - localized area of depolarization of the plasma membrane
that travels in a wave-like manner along an axon
When an action potential reaches the end of a synapse, the signal is transformed into a chemical
signal with the release of a neurotransmitter, process called synaptic transmission
Structure of the Neuron
Basic functional and structural unit of nervous system is the neuron
Structure of these cells is highly specialized to transmit and process action potentials
Neurons have a central body, the soma, which contains the nucleus and is where most of the
biosynthetic activity takes place
Slender projections, called axons and dendrites, extend from the cell
Neurons have 1 axon and many dendrites
o 1 dendrite = bipolar
o Many dendrites = multipolar
Neurons generally carry action potentials in one direction, with dendrites receiving signals and
axons carrying action potentials away from cells body
Axons can branch multiple times and terminate in synaptic knobs
o Chemical messengers are released and travel across a very small gap called the synaptic
cleft to the target cells
The Action Potential
Resting membrane potential
o An electric potential across the plasma membrane of approximately -70 millivolts (mV)
o The interior of the cell is negatively charged with respect to the exterior
Na+/K+ ATPase
o Pumps 3 Na+ out
o 2 K+ in
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