BIL 150 Chapter Notes - Chapter 15: Cri Du Chat, Chromosomal Translocation, Sister Chromatids
28 Apr 2016
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Chromosome theory of inheritance said mendelian genes have specific loci on chromosomes and that chromosomes undergo segregation and independent assortment. Morgan proved chromosomes were location of mendel"s heritable factors: fruit flies with red eyes and got a white eyed male. White eyes only occurred in male fruit flies. Grasshoppers and cockroaches have xx and x0 (male) sex chromosomes. Females come from fertilized eggs (diploid) and males from unfertilized eggs (males have no father and are haploid) Recessive sex linked women need 2 copies, men need only one (one x)= men more x- linked disorders. Disorders like colorblindness, hemophilia and muscular dystrophy sex linked. One of females x becomes inactivated during embryonic development and becomes a. If female heterozygous for particular gene on x, she will be mosaic (cats and black and orange fur) (has both types of cells so both phenotypes expressed)
