PSYC 2051 Chapter Notes - Chapter 9: Blind Experiment, Dsm-5, Toyota Racing Development
Document Summary
Suicide presentation: suicide ideation & behavior, a new hypothesis, and means for mitigation know yet? What if a suicide is a failure of some mechanism we do not. Suggested use of the term suicide ideation & behavior for the suicide phenomena. Complete suicide: no animal model, more than one module or language (thoughts, feelings, behavior) What do we already know: an unknown (or not known well enough) disease; which is common & deadly, research is problematic. 1st incidental finding: ketamine for cholecystectomy can elevate mood: ketamine: an anesthesiologic drug, vast clinical usage. Veterinary usage: illicit drug use, ketamine"s mechanism of action: ketamine blocks glutamate (glutamate=major excitatory neurotransmitter) & is a nmda receptor antagonist. **in depression, there is over activation of the glutamatergic system*: ketamine & depression, in 2000, an article was published about the qualities of ketamine as an antidepressant. This mechanism of action was completely different from other antidepressants- ketamine was rapidly acting (within hours).
