MCD BIO C141 Chapter Notes - Chapter N/A: Receptor Tyrosine Kinase, Sequence Motif, Homeobox
2 Apr 2020
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Plants and animals have similarities between one another in pattern formation and cell-cell communication. Animals: segmental identity is established by the spatially specific transcriptional activation of an overlapping series of master regulatory genes, the hox homeobox genes. Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of "position", ensuring that the correct structures form in the correct places of the body. One of the drosophila mads box family members, mef2, is primarily involved in muscle differentiation (as are its homologs in mammals) (20, 21); the other is involved in wing vein and tracheal development. In drosophila, the dorsal-ventral axis of the embryo is established by a relay of signals between the embryo and its surrounding follicle cells, with ligands traveling through the perivitelline space.
