BIOL 1107 Chapter Notes - Chapter 16: Phenotype, Chromosome, Nuclease
Document Summary
James watson and francis crick made dna model out of metal and wire. Morgan 1908: genes are located on chromosomes made of dna. The search for the genetic material: scientific inquiry. Morgan 1908 showed genes are part of chromosomes. Dna and protein leading candidates for the genetic material. Proteins a class of macromolecules heterogeneity specificity of function. In 1940s biochemists identifies proteins as class of macromolecules. Griffith 1928: discovered that dna can transform nonpathogenic bacteria into pathogenic ones. Killed pathogenic bacteria with heat mixed cell remains with living bacteria of non pathogenic living cells become pathogenic (harmful) S cell is pathogenic kills mouse; r cell is nonpathogenic healthy mouse. Heat kills s cell and becomes nonpathogenic healthy mouse. Killed s cells (nonpathogenic) mix with r cells (nonpathogenic) kills mouse. S cells were nonpathogenic after heated, however transformed r bacteria into pathogenic s bacteria (reproduced more) Heritable substance from dead s cell made r pathogenic.
