DGS 3223 Chapter Notes - Chapter 1: Chromatin, Pinkel, Congenital Disorder
8 Sep 2016
School
Department
Course
Professor
Document Summary
Avery welch medical cytogenetics prelim 1 chapter 1 intro to cytogenetics: avery, maccloud & mccarty 1944. Determined that dna caused the bacterial transformation: tc hsu 1952. Used hypotonic solution to treat metaphases: watson & crick 1953. Dna double helical structure: maurice wilkins 1953. X ray crystallographer that received nobel prize with watson & crick: rosalind franklin. X ray crystallographer whose findings were critical to the success of watson & crick: tijo & levan 1956. Established the correct chromosome number in humans: jerome lejeune 1959. Down syndrome caused by extra chromosome 21: ford 1959. 45,x = turner syndrome: jacobs & strong 1959. Jacobs also reported a case of triple x in 1959: trisomy 13 (pateau syndrome) 1960, trisomy 18 (edwards syndrome) 1960, fritz fuchs & polv riis 1960. First to report use of a prenatal genetic test on amniotic fluid. Barr body (sex chromatin) test for sex determination in a carrier of hemophilia: peter hungerford & nowell 1960.
