DGS 3223 Chapter Notes - Chapter 6: Cytogenetics, Chromosomal Translocation, Semicolon

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Centromere: the centromere is designated 10 (one zero, not ten), but this designation is never indicated on the idiogram. Not a band; a virtual reference point: the portion of the centromere facing the short arm is designated p10. Never indicated in idiograms, but used in nomenclature; they are not bands: the portion of the centromere facing the long arm is designated q10. Never indicated in idiograms, but used in nomenclature; they are not bands: black and gray bands are giemsa-positive heterochromatin, white bands are giemsa-negative euchromatin, giemsa-trypsin staining detects bands at 5 different levels. Band level when you cut a karyogram, you count bands; across the 23 chromosomes, there are ____ bands (ie. 300 bands level 300, 400 bands level 400, etc. ) In parentheses: within another set of parentheses. Band: parentheses indicate the chromosome or chromosomes are involved in a structural rearrangement, parentheses are never used when referring to normal chromosomes, (9)(q34) at 400 band level.

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