PNB 2250 Chapter Notes - Chapter 7: Respiratory Pigment, Carbonic Anhydrase, Inositol
15 Sep 2016
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Intracellular location of transport proteins: better control, smaller size, different environment homeostasis, cell shape can be altered. Increased surface area and volume: outside of cell, proteins are rapidly destroyed. Small cells put respiratory pigment closer to gas outside cells: around 7 nm in diameter, makes diffusion more efficient, increases surface and volume. Comparative physiology & dissociation curves of gas transport. Curves can be right or left-shifted: higher or lower affinity, affected by. Increasing temp acts to decrease protein affinity for oxygen. Temp increases as a consequence of cellular metabolism. Inorganic molecules: tuned to the environment an animal finds itself in. Bohr effect: increased acidity and lowered ph acts to decrease affinity, not all hemoglobin has the same response to acid, animals can have sensitive/insensitive affinity/bohr effect. Root effect in fish: increased acid or carbon dioxide results in loss of oxygen from hemoglobin, used primarily to make oxygen available to swim bladders, insignificant for delivery of oxygen to tissues.
