BIPN 102 Chapter Notes - Chapter 22: Anorexia Nervosa, Adipose Tissue, Neuropeptide Y

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Appetite and satiety: digestive system doesn"t regulate energy intake. Fat store increase -> adipose secretes leptin -> food intake decreases: synthesized under control of obese (ob) gene, neuropeptide y (npy): brain neurotransmitter. Stimulus for food intake: leptin inhibits npy, other neuropeptides, hormones, and adipocytokines also influence npy, leptin release, and the hypothalamic centers controlling food intake, ghrelin: secreted by stomach during fasting. Increases hunger: also promotes release of growth hormone, cck and glp-1: released by gut during meal. Amount of lean muscle mass: muscle has higher oxygen consumption than adipose tissue: 3. Activity level: higher levels increase metabolic rate: 4. Diet: metabolic rate increases after a meal (diet-induced thermogenesis). Hormones: metabolic rate increased by thyroid hormones and catecholamines (e/ne: 6. Each pound stores 3500 kcal: adipose tissue efficient at storing large amounts of energy in minimal space, energy harder to access, so metabolism is slower than carb metabolism. Products of digestion are being absorbed, used, and stored.

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