PHYSIOL 201 Chapter Notes - Chapter 15: Hbb, Cardiac Output, Hemoglobin
27 Feb 2019
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Hemoglobin: normal blood hb = 15 gm/dl, hemoglobin is a protein with 4 peptide chains- 2 alpha and 2 beta subunits and 4 heme groups containing iron. Globin : each heme has an iron atom (fe2+) at the center to which the o2 molecules bind. Each hemoglobin molecule can bind 4 molecules of. Venous blood po2 = 40mmhg due to the delivery of o2 to the tissues. It binds to the alpha and beta globin peptides. This is 30% of all co2: 3) co2 is also converted to hco3 (bicarbonate) and carried in the blood as bicarbonate ions. This is 60% of all co2 in the blood: pco2 in tissues > pco2 in blood since tissues are creating co2 by cellular metabolism. Co2 diffuses from cells to isf to plasma to rbcs: within the rbcs there is an enzyme called carbonic anhydrase. The enzyme catalyzes both the forward and reverse reaction converting co2.
