BIOCHEM 420 Chapter Notes - Chapter 8: Reaction Rate, Enzyme, Metal

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Catalysis is essential to making most critical biochemical reactions proceed at useful rates under physiological conditions. Ability to lower the free energy of the transition state for the reaction being catalyzed: 1 enzymes as biological catalysts. Catalyst : substance that increases the rate , or velocity , chemical reaction without itself being changed in the overall process. Substrate : substance that is acted on by an enzyme. The rate of a favorable reaction depends greatly on whether a catalyst is present and on the nature of the catalyst. * catalysts increases the velocity of chemical reactions of a (cid:8869) enzymes are biological catalysts. Although a true catalyst participates in the reaction process, it is unchanged by the process. Catalysts change rates of processes but do not affect the thermodynamic favorability of a reaction (cid:8869) equilibrium state is approached more quickly in the presence of a catalyst.

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