BIOL 1141 Chapter Notes - Chapter 9: Programmed Cell Death, Sister Chromatids, Spindle Apparatus

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G1 phase: cell recovers from the previous division, cell grows in size, increases the number of organelles, and accumulates materials that will be used for dna synthesis. S phase: dna synthesis or replication occurs. G2 phase: cell synthesizes the proteins that will assist cell division, microtubules used to form the mitotic spindle. M phase: mitosis and cytokinesis, when division of cytoplasm is complete, two daughter cells are present. Cyclins: internal signaling proteins that increase and decrease as the cell cycle continues. Mitosis: a 2n nucleus divides to produce daughter nuclei that are also 2n. Prophase: chromatin has condensed and chromosomes are visible, parental chromosomes are already duplicated and composed of two sister chromatids held together at a centromere, nucleolus and nuclear envelope disappears. Prometaphase: kinetochores appear on each side of the centromere and attach sister chromatids to the kinetochore spindle fibers. Metaphase: the centromeres of chromosomes are now in alignment at center of cell.

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