BIO 311 Chapter Notes - Chapter 2: Antoine Lavoisier, Atomic Number, Bond Length

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Chemical Basis of Life
• Laoisie -1794) otasted the heial sipliit of the ieal
oldith opleit of plat ad aial olds
• Latte oposed of opouds ih i ao, hdoge, oge,
nitrogen, sulfur, and phosphorous (the six most abundant elements in
living systems)
• Eal th etu ioheial iestigatios of gluose eakdo i
yeast and animal muscle cells revealed remarkable chemical similarities
• Jaues Mood - What is tue of E. oli is tue of a elephat
• Theo that all ogaiss shae a oo eolutioa oigi is ased, i
part, on our biochemical unity
• Bioheial Uit- the ioheial opositio ake-up of all
organisms is astoundingly similar
The Chemical Basis of Life
• Fee tha  of the more than 90 naturally occurring chemical elements are
essential to all organisms
• Bulk eleets shaded i oage ae stutual opoets of all ells ad tissues ad
are required in the diet in gram quantities
• Tae eleets shaded i ello equired in much smaller quantities (<< a few
milligrams)
Carbon Chemistry
• Cheist of liig ogaiss eoles aoud ao
• C aouts fo >half the d eight of ells
• C fos sigle ods ith H, ad sigle ad doule ods ith O ad N
• C a also form very stable single bonds with up to four other Cs***
• To Cs a shae to o thee eleto pais, foig doule o tiple
bonds
• The easo fo this is that C, ith a atoi ue of , has a ale
of 4, i.e. 4 electrons to form covalent bonds
1s2, 2s2, 2px
1
, 2py
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1
, 2pz
 ↔ s, s
, 2px
1
, 2py
1
, 2pz
1
The periodic table of the elements
Geometry of Carbon Bonding
• C atos hae a haateisti tetahedal aageet of thei fou sigle ods:
bond angle ~109.5º and bond length 0.154 nm
• “igle ods hae osideale feedo of otatio, as sho fo ethae CH
• C=C doule ods uh shote . , ae igid, ad the atos desigated A,
B, X, and Y all lie in the same rigid plane - planar
Geometry of C-Bonding
• High feedo of otatio leads to geat diesit i iooleule foatio
! Linear chains
! Branched chains
! Cyclic structures
• Bodig esatilit of C a ajo fato i the seletio of C opouds
during evolution of living organisms
• No othe eleet a fo oleules of suh idel diffeet sizes,
shapes and composition
• Vast ajoit of iooleules ae deiaties of hdoaos, ith H
atoms replaced by a variety of functional groups
• Futioal goups ofe chemical properties on the molecule
Geometry of C-Bonding
• C has uiue popet of eig ale to od to itself i log hais
• Ee a fou C hai has thee diffeet possile skeletos
• Allos a diffeet opouds to e foed  eaageet ad not resynthesis***
• Addig just oe O o doule od a poide a diffeet stutues, eah
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Document Summary

B, x, and y all lie in the same rigid plane - planar. Geometry of c-bonding: high f(cid:396)eedo(cid:373) of (cid:396)otatio(cid:374) leads to g(cid:396)eat di(cid:448)e(cid:396)sit(cid:455) i(cid:374) (cid:271)io(cid:373)ole(cid:272)ule fo(cid:396)(cid:373)atio(cid:374) Acetyl-coenzyme a: ca(cid:396)(cid:396)ie(cid:396) of a(cid:272)et(cid:455)l g(cid:396)oups, (cid:272)o(cid:374)tains multiple functional groups, pa(cid:272)e filli(cid:374)g (cid:373)odel, n is (cid:271)lue, c is (cid:271)la(cid:272)k, p is o(cid:396)a(cid:374)ge, o is (cid:396)ed, Retina nerve impulses: e(cid:374)e(cid:396)g(cid:455) of a(cid:271)so(cid:396)(cid:271)ed light (cid:272)o(cid:374)(cid:448)e(cid:396)ts (cid:1005)(cid:1005)-cis-retinal to all-transretinal, triggering electrical changes that lead to a nerve impulse. The concept of biochemical unity refers to the fact that the chemical composition of all organisms is highly similar: true, false. The 6 most abundant elements in biological systems are: c, h, cl, mg, o, n, h, na, k, mg, o, p, na, h, o, c, p, s, c, h, o, n, s, p. 6co2 + 6h2o + light c6h12o6 + 6o2: no(cid:374)-photosynthetic organisms consume these carbohydrates as a source of energy. The use of thermodynamics in biology has a long history rich in confusion.

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