BIO 325 Chapter Notes - Chapter 8: Nonsense Mutation, Glutamine, Reading Frame

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12 Oct 2018
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Chapter 8 problems: the following diagram describes the mrna sequence of part of the a gene and the. Alalysglutrpasnasnserleulysthrlysleu beginning of the b gene of phage x174. In this phage, some genes are read in overlapping reading frames. For example, the code for the a gene is used for part of the b gene, but the reading frame is displaced by one base. Shown here is the single mrna with the codons for proteins a and b indicated. aa# 5 6 7 8 9 10 11 12 13 14 15 16. Given the following amino acid (aa) changes, indicate the base change that occurred in the mrna and the consequences for the other protein sequence: asn at position 10 in protein a is changed to tyr. If the asn (5" aac) is changed to a tyr residue, the nucleotide change is to a uac. In protein b this means that the gln (5"

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