BSCI 1001 Chapter Notes - Chapter 5: Golgi Apparatus, Infobase Publishing, Nuclear Pore

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The nucleus is considered to be the headquarters of the cell. It is the organelle that is the easiest to see with an average diameter of 5um. The nucleus is enclosed from the cytoplasm by a nuclear envelope. The nuclear envelope is a double membrane of lipid bilayer that contains associated proteins. The membrane is perforated by pore structures, and at the lip of each pore, the inner and outer membranes of the nuclear envelope are continuous. The pore complex regulates the entry and exit of most proteins and rnas, as well as large complexes of macromolecules. Also involved with the nuclear envelope, is the nuclear lamina, which is a netlike array of protein filaments that maintains the shape of nucleus by mechanically supporting the nuclear envelope. There is also evidence for a nuclear matrix, which is a framework of fibers extending throughout the nuclear interior. The nucleus contains most the genes (some are in the mitochondria and chloroplasts. )

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