BIOL122 Lecture 4: Week four drug list
Document Summary
Without prostaglandins your body cannot produce the protective mucous lining generally found in your gi system. Thus gi haemorrhages (bleeding) and ulcers can occur. Taken orally and thus undergo first pass metabolism. Drugs given to lower cholesterol levels in the blood. Less cholesterol levels will hopefully lead to less formation of atherosclerosis. This decreases the amount of cholesterol made by your liver. Thus reducing your risk of forming further atherosclerotic plaques. Statins also increase the number of ldl receptors on the liver. This means circulating ldls will be taken up by the liver. Thus ldls will be removed from the blood stream. Thromboxane a2 is vital for attracting platelets. Basically when the blood vessel walls get damaged they would normally send out these really cool party invitations (chemotaxis) inviting all the platelets to come around and party (form a platelet plug). Aspirin however shuts down (competitively inhibits) the party- invitation-making factory (cox 1 and.
