BIOL3190 Lecture Notes - Lecture 7: Inflammatory Bowel Disease, Ulcerative Colitis, Twin
Document Summary
Went to usyd , medicine, physician training -> gastroenterology. Can go anywhere with medicine -> research science and clinical medicine. Research into crones disease at the hospital -> have patient contact. Idiopathic inflammation -> without known cause e. g. multiple sclerosis, inflammatory bowel disease. Imaging to the area most commonly inflamed is difficult -> between the small and large bowel. Ibd is diagnosed in young people, mean age is 27. Starts in rectum and into the rest of the colon. Developing drugs that inhibit cytokines -> breakthrough in idiopathic disease treatment. Available in clinical trials (half people get the drug and half get placebo) The patients responded well (60-70%) -> still some people that can"t be treated. Half of identical twins both had crohn"s disease. 1/21 of fraternal twins both had crohn"s disease. Chron"s disease has a genetic component, and an environmental component. Medicine can investigate new therapies; scientists also look at.
