KNH 411 Study Guide - Final Guide: Inflammatory Bowel Disease, Etiology, Catabolism
17 Dec 2018
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Inflammatory bowel disease is characterized as an autoimmune, chronic inflammatory condition of the gastrointestinal tract: ibd = general term for, ulcerative colitis, crohn"s disease. Incidence of ibd = 5-15 per 100,000 people: prevalence of ibd = estimated to be 388-444 per. 100,000 people: fairly equal in both males and females, higher in caucasians and those with ashkenazi. Typically occurs in patients who are 15-30. Both: diarrhea, fever, weight loss, anemia, food intolerances, malnutrition, growth failure, etc. Montreal classification system: used to describe the clinical and endoscopic presentation of both crohn"s and ulcerative colitis: truelove and witts criteria are used to determine the severity of uc. Testing for markers of ibd: serum levels of cytokines, c-reactive proteins. Lab results found to be indicative of exacerbations of ibd: calprotectin (cal), lactoferrin (lf) and polymorphonuclear neutrophil elastase levels in the stool, exacerbations of crohn"s disease can also be evidenced by low albumin and elevated wbc levels.
